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Halogen facilitates the binding with the enzyme because it increases the binding affinity and binding selectivity, and adding halogens to lead during drug development is well recognized to be a general optimizing approach [31]

When combined with targeted nutrition, lifestyle adjustments, and other regenerative treatments, it offers a well-rounded strategy for addressing heavy metal exposure

Huang K, Li Z, He X, Dai J, Huang B, Shi Y, et al

The aberrant distribution of BAP1 in glioma cells existing in both the nucleus and cytoplasm represents a potential new research target